Scientific Programme

11:30 – 12:30

Conference registration, pizza lunch, divide into groups

12:30 – 14:45

Group 1 (Advanced group)

Hands-on training on QExactive and Eclipse mass spectrometers. Instrument discussions and networking

Group 2 (Beginners group)

Workshop covering introduction to native MS, sample preparation tips and tricks.

14:45 – 15:15

Coffee Break

15:15 – 17:30

Group 2 (Beginners group)

Hands-on training on QExactive and Eclipse mass spectrometers. Instrument discussions and networking

Group 1 (Advanced group)

Advanced workshop covering development on UHMR and cyclicIMS, ion paths. Which parameters are important and why?

17:30 onwards

Informal networking event – near The Exchange, Birmingham City Centre (location TBD)

9:00 – 9:45

Conference Registration

Session 1 (Chair: Aneika Leney, University of Birmingham)

9:40 – 9:45

Welcome and Introduction to BMS-SIG

9:45 – 10:30

Keynote Lecture

Idlir Liko (Omass Therapeutics): Native MS takes the central stage - Enabling the development of novel medicines

10:30 – 10:45

Ikhlas Mohamed Mohamud Ahmed (University of Strathclyde): Ion mobility mass spectrometry unveils conformational effects of drug lead-EPI-001 on the intrinsically disordered N-terminal domain of the Androgen receptor

10:45 – 11:00

Sarah Vickers (University College London/Birkbeck College London): Ion mobility mass spectrometry reveals oligomerisation intermediates in alpha-1 antitrypsin deficiency

11:00 – 11:45

Coffee Break

Session 2 (Chair: Kish Adoni, University College London)

11:45 – 12:00

Niklas Geue (University of Manchester): Lessons from native ion mobility mass spectrometry applied to supramolecular complexes

12:00 – 12:15

Jaspreet Sound (University of Birmingham): Native mass spectrometry is a powerful tool to probe the evolution of photosynthesis in cyanobacteria

12:15 – 12:30

Anthony Devlin (Rosalind Franklin Institute): Structural elucidation of glycosaminoglycans (GAGs) using trapped ion mobility spectrometry (TIMS)

12:30 – 12:45

Poster flash talks (Chair: Joseph Gault, AstraZeneca)

12:45 – 2:00

Lunch and Posters

Session 3 (Chair: Kelechi Uleanya, University of York)

2:00 – 2:15

Dan McGill (Rosalind Franklin Institute): Cold argon plasma for non-enzymatic digestion of proteins and peptides

2:15 – 2:30

Emma Sisley (University of Birmingham): Tissue washing improves native ambient mass spectrometry detection of membrane proteins directly from tissue.

2:30 – 2:45

Glenn Masson (University of Dundee): Structural basis of small molecule PI3kalpha activators via HDX-MS

2:45 – 3:30

Coffee and Posters

Session 4 (Chair: Alice Colyer, University of Leeds)

3:30 – 3:45

Cameron Baines (University of Nottingham): Carbene footprinting of EF-Tu in complex with contrasting Elfamycin antimicrobials

3:45 – 4:15

Keynote Lecture

Frank Sobott (University of Leeds): Molecular Footprints of Proteins

4:15 – 4:30

Closing address and prizes